Fig. 5

CD26⁺CD8⁺ T cells exhibit a greater migratory capacity in CLL. A Representative plots of the frequency of CCR5⁺CD8⁺ T cells among CD26^neg/low/high subsets. B The graphical illustrates the tendency of CCR5⁺CD8⁺ T cells homing to secondary lymphoid organs or inflamed tissues in response to CCL3, MIP-1 \(\alpha\)/\(\beta\), and RANTES. C Cumulative data of the frequency of CCR5⁺CD8⁺ T cells among CD26^neg/low/high CD8 + T cells in CLL. D Representative flow plots of the frequency CCR6⁺CD8⁺ T cells among CD26^neg/low/high subsets. E The graphical illustrates the tendency of CCR6⁺CD8⁺ T cells homing to colon, and mucosal tissues in response to CCL20. F Cumulative data of the frequency of CCR6⁺CD8⁺ T cells among CD26^neg/low/high. G Representative plots of the frequency of CCR7⁺CD8⁺ T cells among CD26^neg/low/high subsets of CD8⁺ T cells. H The graphical illustrates the tendency of CCR7⁺CD8⁺ T cells homing to lymph nodes in response to CCL19. I Cumulative data of the frequency of CCR7⁺CD8⁺ T cells among CD26^neg/low/high subsets. J Representative plots of the frequency of Cutaneous Lymphocyte Antigen (CLA)⁺CD8⁺ T cells among CD26^neg/low/high cells. K The graphical illustrates the tendency of CLA⁺CD8⁺ T cells homing to skin following E/P Selectin binding on endothelial cells. L Cumulative data of the frequency of CLA⁺CD8⁺ T cells among CD26^neg/low/high cells. M Representative plots, and the frequency of migrated CD26^neg, CD26^low, and CD26^high CD8⁺ T cells at the baseline and after 18 h in response to (N) Fetal Bovine Serum (FBS-10%), (O) RANTES (10 nM), and (P) IL-18 (100 ng/ml). Error bars represent the median with an interquartile range. Each dot represents an individual human sample.