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Fig. 1 | Experimental Hematology & Oncology

Fig. 1

From: Caspase-8 contributes to an immuno-hot microenvironment by promoting phagocytosis via an ecto-calreticulin-dependent mechanism

Fig. 1

The correlation of CASP8 transcription and the 18 gene set ICB predictive biomarker. A total of 4874 patients across 31 cancer types from TCGA were enrolled for analysis. a GSEA comparing T cell-inflamed gene sets (measurement of ICB-responsiveness) between CASP8 -low and CASP8-high patients in TCGA. b Enrichment score of the T cell-inflamed gene set across 31 TCGA datasets. c Heatmap of the expression of 18 genes in the T cell-inflamed gene set in CASP8-low and CASP8-high patients. The 1st and 4th quartiles were defined as CASP8-low and CASP8-high, respectively

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Experimental Hematology & Oncology

ISSN: 2162-3619

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