Fig. 7

High expression of PAQR4 is associated with poor prognosis in HCC. A PAQR4 expression in the normal and HCC data were obtained from TCGA and the (B, C) Kaplan–Meier survival curves disease-free survival of patients with HCC from TCGA. D PAQR4 expression in human HCC data were obtained from 6 GEO datasets. E PAQR4 expression in DEN-induced mouse liver cancer. F Representative images of Immunohistochemistry (IHC) from human HCC samples and the expression of PAQR4 was compared between Adjacent tissue and tumor tissue according to the IHC scoring. G, H Kaplan–Meier survival curves and disease-free survival of patients with HCC from Tongji cohort. i Schematic representation of a model for the role of PAQR4 in HCC. *P < 0.05, **P < 0.01, ***P < 0.001