Fig. 1

Identification of IGPI and its clinical applications. A volcano plot showing differentially expressed genes between tumor and normal samples; B modules and phenotype showing the tumor-related genes; C Venn diagram showing the intersection of differentially expressed genes, tumor-related genes and immune-related genes; D univariate and multivariate COX regression analysis of candidate genes; E COX regression analysis of clinical and genomic parameters; F time-dependent ROC curve of IGPI score; G analysis of metastasis free survival between high and low risk groups in the GSE116918; H analysis of biochemical recurrence free survival between high and low risk groups in the GSE116918; I ROC curve showing the diagnostic ability of metastasis in the GSE21034; J analysis of metastasis free survival between high and low risk groups in the GSE134051; K analysis of progression free survival between high and low risk groups in the TCGA database; L ROC curve showing the diagnostic ability of radiation resistance in the GSE53902; M comparison between Gleason score and IGPI score; N comparison between T stage and IGPI score; O comparison between biochemical recurrence and IGPI score. IGPI = immunologic gene prognostic index; ROC = receiver operating characteristic. ns, p ≥ 0.05; *p < 0.05; **p < 0.01; ***p < 0.001