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Fig. 5 | Experimental Hematology & Oncology

Fig. 5

From: CDCA8 induced by NF-YA promotes hepatocellular carcinoma progression by regulating the MEK/ERK pathway

Fig. 5

Knockdown of CDCA8 inhibited tumor growth and pulmonary metastasis in vivo. a Bel-7402 cell with different CDCA8 expression were subcutaneously transplanted the xenograft into BALB/c nude mice (n = 6 for shCDCA8; n = 5 for shCtrl) b Tumor weights and c tumor sizes were measured. d Tumors were stained by Ki-67. e The number of lung metastasis in different groups were measured. f HepG2 and g Huh7 cells with different CDCA8 expression were injected into BALB/c nude mice (n = 6 for each group) through the tail vein to establish lung metastasis models. (*p < 0.05; **p < 0.01; ***p < 0.001)

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Experimental Hematology & Oncology

ISSN: 2162-3619

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