Table 1 Correlation between CTPS2 protein expression and clinicopathologic parameters of chronic lymphocytic leukemia (CLL) patients from Shandong Provincial Hospital CLL (SPHCLL) database

Age(years)

  < 60

33

16

17

  ≥ 60

35

17

18

Gender

 Male

44

22

22

 Female

29

14

15

WBC Count (*10⁹/L)

  < 40

46

22

24

  ≥ 40

24

11

13

Rai stage

 Low risk

42

19

23

 High risk

14

4

10

Binet stage

 Stage A or B

38

17

21

 Stage C

15

5

10

IGHV mutation

 Mutated

17

12

5

 Unmutated

6

1

5

ZAP 70

 Positive

4

1

3

 Negative

30

9

21

CD38

 Positive

4

2

2

 Negative

36

14

22

Serum LDH

 Normal

50

22

28

 Elevated

14

8

6

Serum β2-MG

 Normal

36

15

21

 Elevated

31

15

16

17p

 Normal

36

14

22

 Deletion

4

2

2

FISH

Favorable: normal,13q-, trisomy 12

23

10

13

Unfavorable: 11q- and/ or 17p-

14

3

11