Fig. 3
From: Understanding the versatile roles and applications of EpCAM in cancers: from bench to bedside
Changes and developments of EpCAM in metastasis, detection and immunotherapy. a Dynamic expression of EpCAM in EMT process of cancer cells. b EpCAM related CTC detection methods, advantages and their limitations. c Development of EpCAM mediated immunotherapies. ADC antibody–drug conjugate, ADCC antibody-dependent cell-mediated cytotoxicity, CDC complement-dependent cytotoxicity, CRS cytokine release syndrome