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Table 1 Correlation between circRanGAP1 and clinicopathological characteristics in 40 HCC patients

From: circRanGAP1/miR-27b-3p/NRAS Axis may promote the progression of hepatocellular Carcinoma

Characteristic

circRanGAP1 High

circRanGAP1 Low

p

No. patients

20

20

 

Age, n (%)

0.514

 < 55

9 (22.5%)

6 (15%)

 

 >= 55

11 (27.5%)

14 (35%)

Sex, n (%)

1.000

 Female

5 (12.5%)

4 (10%)

 

 Male

15 (37.5%)

16 (40%)

 

Tumor number, n (%)

0.695

 >= 2

3 (7.5%)

5 (12.5%)

 

 1

17 (42.5%)

15 (37.5%)

 

Tumor size, n (%)

0.048

 < 5cm

4 (10%)

11 (27.5%)

 

 >= 5cm

16 (40%)

9 (22.5%)

 

Pathologic stage, n (%)

0.001

 I-II

4 (10%)

15 (37.5%)

 

 III-IV

16 (40%)

5 (12.5%)

 

Microvascular invasion, n (%)

0.333

 No

6 (15%)

10 (25%)

 

 Yes

14 (35%)

10 (25%)

 

S grade, n (%)

0.527

 S1-2

8 (20%)

11 (27.5%)

 

 S3-4

12 (30%)

9 (22.5%)

 

HBsAg, n (%)

1.000

 Negative

4 (10%)

4 (10%)

 

 Positive

16 (40%)

16 (40%)

 

HCVAb, n (%)

1.000

 Negative

1 (2.5%)

2 (5%)

 

 Positive

19 (47.5%)

18 (45%)

 

ALT, U/L, n (%)

0.695

 <=75

15 (37.5%)

17 (42.5%)

 

 >75

5 (12.5%)

3 (7.5%)

 

AFP, ng/ml, n (%)

0.320

 <=20

5 (12.5%)

9 (22.5%)

 

 >20

15 (37.5%)

11 (27.5%)

 
  1. AFP alpha-fetoprotein, HBsAg hepatitis B surface antigen, HCVAb hepatitis C virus antibody, ALT aLanine aminotransferase
  2. *p < 0.05 was regarded as statistically significant, the p-value was calculated using Cox proportional hazards regression. Bold p-value was regarded as statistically significant.