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Fig. 9 | Experimental Hematology & Oncology

Fig. 9

From: circRanGAP1/miR-27b-3p/NRAS Axis may promote the progression of hepatocellular Carcinoma

Fig. 9

NRAS+ and CD68+ TAMs have prognostic value for patients with HCC. A and B. IHC analysis showed that patients with high circRanGAP1 expression had high ki67, NRAS, and CD68 protein expression, whereas those with low circRanGAP1 expression had low ki67, NRAS, and CD68 protein expression. C. TCGA data reveal the expression of NRAS and the relationship between NRAS and CD68 in HCC tissues. D. Kaplan-Meier analysis reveals the prognostic value of NRAS and CD68+ TAMs. E. The proposed model illustrates the circRanGAP1–miR-27b-3p/NRAS signaling function in the regulation of HCC progression

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