Fig. 8From: circRanGAP1/miR-27b-3p/NRAS Axis may promote the progression of hepatocellular CarcinomacircRanGAP1 is correlated with tumor-associated-macrophage (TAM) infiltration. A. Fluorescence-activated cell sorting (FACS) analysis to confirm the infiltration of F4/80+ TAMs in Hep1-6-circRanGAP1 xenografts and Hep1-6-Mock xenografts via a subcutaneous xenograft tumor model. B. Confirmed the NRAS expression, ki67 expression, and F4/80+ TAMs infiltration in the Hep1-6-circRanGAP1 group compared with that in the Hep1-6-Mock group through IHC analysis. C. IHC analysis was performed for detecting the expression level of NRAS, ki67 expression, and F4/80+ TAMs infiltration after treating with miR-27b-3p mimic. *P < 0.05; **P < 0.01; ***P < 0.001; NS not significantBack to article page