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Fig. 2 | Experimental Hematology & Oncology

Fig. 2

From: Pan-cancer landscape of aberrant DNA Methylation across childhood Cancers: Molecular Characteristics and Clinical relevance

Fig. 2

Potential prognostic significance of SDMCs. (a) Kaplan-Meier survival curves display a significant difference in overall survival between the two groups (high score versus low score) in neuroblastoma (NBL, n = 209), primitive neuroectodermal tumor (PNET, n = 88), and Wilms tumor (WT, n = 108). For each cancer, we used the following prognostic index to generate high- and low-score pediatric cancer patient groups. (b) Forest plots of unadjusted and adjusted hazard ratios of an elevated SDMC score for NBL, PNET, and WT. (c) Kaplan-Meier survival curves display a significant difference in overall survival between the two groups (high score versus low score) in osteogenic sarcoma (OGS, n = 84) and rhabdoid tumor (RT, n = 39), which are pediatric cancers that were not used to identify SDMCs. (d) Forest plots of unadjusted and adjusted hazard ratios of an elevated SDMC score for OGS and RT.

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Experimental Hematology & Oncology

ISSN: 2162-3619

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