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Fig. 2 | Experimental Hematology & Oncology

Fig. 2

From: Polyclonal evolution of Fanconi anemia to MDS and AML revealed at single cell resolution

Fig. 2

Schematic model of clonal evolution across patient P1001 disease progression. A Somatic mutation burden in peripheral blood and bone marrow samples from patient P1001 at different stages. B Correlation between variant allele frequency (VAF) in peripheral blood samples and bone marrow samples of patient P1001 (The Pearson correlation: 0.7; P = 0.0013). C Cellular prevalence in bone marrow samples of patient P1001. D Frequency of mutations in different clones from patient P1001 at different stages. E A model of clonal evolution based on the average value for the cellular prevalence in each cluster at each stage of progression

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