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Fig. 3 | Experimental Hematology & Oncology

Fig. 3

From: Multi-omic profiling of the leukemic microenvironment shows bone marrow interstitial fluid is distinct from peripheral blood plasma

Fig. 3

Proteins enriched in the BMIF are localized in extracellular vesicles and exosomes. A Compartment differences at leukemia (BMIFdx vs PBPdx). B Compartment differences after induction therapy (BMIFd29 vs PBPd29). Both volcano plots show–log10 adjusted p-value and log2 coefficient of each protein after limma analysis. Dashed lines mark the cut-offs for significance in their respective intercepts. C Subcellular localization according to COMPARTMENTS enrichment analysis of all proteins enriched in the BMIF at diagnosis or after induction therapy. D Comparison of the metabolic enzymes that were enriched in the either leukemic or post-induction BMIF

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Experimental Hematology & Oncology

ISSN: 2162-3619

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