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Fig. 2 | Experimental Hematology & Oncology

Fig. 2

From: Multi-omic profiling of the leukemic microenvironment shows bone marrow interstitial fluid is distinct from peripheral blood plasma

Fig. 2

Integration of data reveals that multiple analytes differ between BMIF and PBP. Uniform Manifold Approximation and Projection (UMAP) of all analytes (normalized and z-score scaled) after training using significant analytes. Individual analytes are annotated based on A fuzzy c-means cluster membership or B analyte class. For the cluster membership plot, dotted lines were draw to indicate separation between experimental groups. C Radar plots showing intensity of the analytes in each cluster. Z score-scaled intensities were plotted and annotated based on the analyte’s cluster membership score. Color intensity reflects the cluster score and analytes with scores < 0.5 are omitted

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