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Table 1 Correlation between circRIC8B expression and clinical characteristics in 63 CLL patients

From: CircRIC8B regulates the lipid metabolism of chronic lymphocytic leukemia through miR199b-5p/LPL axis

Characteristic

All cases

circRIC8B

Chi-square

P value

low

high

All cases

63

31

32

  

Age

  ≤ 65y

44

21

23

0.026

0.871

  > 65y

18

9

9

  

Sex

 Male

43

21

22

0.007

0.932

 Female

20

10

10

  

Rai stage

 0

2

1

1

0.587

0.444

 I-II

29

12

17

  

 III-IV

28

15

13

  

Binet stage

 A

27

13

14

0.021

0.886

 B/C

34

17

17

  

TP53 abnormality

 Absent

46

25

21

1.999

0.157

 Present

15

5

10

  

IGHV status

 Unmutated

30

11

19

5.670

0.017*

 Mutated

33

22

11

  

Trisomy 12

 Absent

42

19

23

0.003

0.954

 Present

13

6

7

  

Del(13q)

 Absent

30

16

14

1.652

0.199

 Present

25

9

16

  

ATM deletion

 Absent

46

22

24

0.020

0.887

 Present

11

5

6

  

Cytogenetics

 Diploid

35

14

21

1.586

0.208

 Complex

19

11

8

  

β2-MG

  ≤ 3.5 mg/L

27

13

14

0.021

0.886

  > 3.5 mg/L

34

17

17

  
  1. IGHV immunoglobulin heavy-chain variable region, Del deletion, β2-MG β2-microglobulin
  2. *P < 0,05