Fig. 5
From: CircRIC8B regulates the lipid metabolism of chronic lymphocytic leukemia through miR199b-5p/LPL axis
Clinical significance of biological functions of circRIC8B. A PCA (principal component analysis) score plot, B OPLS-DA (orthogonal projections to latent structures-discriminant analysis,) score plot, and C permutation test of OPLS-DA model between the control group and si-circRIC8B group. D Volcano plot presented the dysregulated metabolites. VIP, variable importance in the projection. E Metabolic pathway mapping of the impacted metabolic network. F, G Photomicrographs and quantitative analysis of Nile red staining. Scale bar, 10 μm. H, I Relative TG (mg/g protein) contents. TG, Triglyceride. Data are shown as means ± SD (n = 3, *P < 0.05, **P < 0.01, ***P < 0.001)