Skip to main content

Table 1 Single-cell transcriptome datasets of PSC-derived cells during hematopoietic differentiation

From: Generation and clinical potential of functional T lymphocytes from gene-edited pluripotent stem cells

Year of publication

Cell types

Dataset ID (data type)

Generating T cell or not (Condition)

Function

2017 [62]

hESC-derived HE, non-HE, and HP cell populations

-(scRNA-seq)

Unknown

Unknown

2017

hiPSC-derived CD34 + cells

GSE87422 (single cell qRT-PCR)

Unknown

Unknown

2020 [63]

CD34 + CD43- derived cells

E-MTAB-8205 (scRNA-seq)

Unknown

Unknown

2020 [64]

CD235a-CD43 + cells

https://lab.antonellafidanza.com (scRNA-seq)

Unknown

Unknown

2020 [65]

iPSC-derived EB at day 9/18/20

GSE134355 (scRNA-seq)

Unknown

Unknown

2020 [63]

iPSC-derived CD34 + /CD43 − cells and their derivatives

E-MTAB-8205 (scRNA-seq)

Unknown

Unknown

2020 [66]

hESCs-derived CD43 + HPCs

GSE148215 (scRNA-seq)

CD8+ T/CD4+ T/CD4+CD8+ T (OP9-DLL4 co-culture)

Unknown

2021 [67]

hPSC/hPSC-derived D2/4/6 cells

GSE145859 (scRNA-seq)

CD3 + T (ATO); CD8 + T(anti-CD3/28 stimulation)

Cytotoxic function in vivo

2021 [68]

CD45 + CD34 + CD7 + iPSC-proT cells

GSE169279

(scRNA-seq)

CD3 + αβ T cells

(DL4-μbeads)

Unknown

  1. iPSC induced pluripotent stem cells, HPSC hematopoietic stem cells, scRNA-seq  single-cell RNA sequencing; HESC; EB; ATO artificial thymic organoid, qRT-PCR quantitative real-time-polymerase chain reaction