Table 3 Genome-wide gene expression profiles of KG1a cells treated with apatinib and chidamide alone or in combination
Gene | Metabolic function | Mean fold change (log2) | Mean FDR |
|---|---|---|---|
MPI | Carbohydrates metabolism | − 3.13 | 1.48E−18 |
MECR | Fatty acids synthesis | − 2.24 | 6.50E−12 |
PLCH1 | Phosphatidylinositol metabolism | − 2.24 | 1.85E−05 |
PIGK | Glycosylphospatidylinositol biosynthesis | − 2.23 | 3.30E−04 |
IDH3B | TCA cycle enzyme | − 2.09 | 4.79E−05 |
GLS | Glutamine metabolism | − 2.07 | 2.70E−04 |
NDUFB3 | Electon transport chain subunit | − 2.06 | 3.53E−09 |
GAMT | Creatine biosynthesis/Fatty acid oxidation | − 2.03 | 3.78E−06 |
ST6GALNAC1 | Protein glycosylation | − 1.88 | 1.83E−05 |
NDUFAB1 | Electron transport chain subunit | − 1.84 | 2.70E−03 |