Physical activity improves outcomes of combined lenvatinib plus anti-PD-1 therapy in unresectable hepatocellular carcinoma: a retrospective study and mouse model

Table 2 Multivariate analysis of the association between baseline factors and treatment outcomes

Variables	No. of patients	Overall survival		Progression-free survival		Objective response
		Multivariate Cox regression				Multivariate Logistic regression
		HR (95% CI)	P value	HR (95% CI)	P value	OR (95% CI)	P value
Regular physical activity
Yes	28	0.203	0.022	0.158	0.004	4.204	0.016
No	31	(0.052–0.794)	0.022	(0.044–0.562)	0.004	(1.302–13.569)	0.016
Macrovascular invasion
Yes	34	5.430	0.03
No	25	(1.183–24.935
INR
> 1.20	15					0.189	0.049
≤ 1.20	44					(0.036–0.992)

CI confidence interval, HR hazard ratio, INR international normalized ratio, OR objective response

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