Cancer type | Target | Gene description | Role | References |
---|---|---|---|---|
GC | PTEN | Phosphate and tension homology deleted on chromosome ten | Tumor suppressor | [39] |
FOXC2 | Forkhead box protein C2 | Oncogene | [46] | |
CRC | miR-1625 | microRNA 6125 | Tumor suppressor | [49] |
GSK3β | Glycogen synthase kinase 3 beta | Tumor suppressor | [49] | |
XIST | X inactivate-specific transcript | Oncogene | [47] | |
Liver cancer | miR-145 | microRNA 145 | Tumor suppressor | [55] |
SOCS2 | Suppressor of cytokine signaling 2 | Tumor suppressor | [54] | |
OCT4 (POU5F1) | POU class 5 homeobox 1 | Oncogene | [53] | |
EGFR | Epidermal growth factor receptor | Oncogene | [36] | |
Serpin E2 | Serpin peptidase inhibitor clade E member 2 | Oncogene | [50] | |
IL11 | Interleukin-11 | Oncogene | [50] | |
PC | YAP | YES-associated protein | Oncogene | [56] |
PER1 | Period circadian regulator 1 | Tumor suppressor | [58] | |
PIK3CB | Phosphoinositide-3-kinase catalytic beta | Oncogene | [57] | |
Lung cancer | 6PGD | 6-phosphogluconate dehydrogenase | Oncogene | [40] |
AXIN1 | axin 1 | Tumor suppressor | [62] | |
Leukemia | TNFRSF1B | TNF receptor superfamily member 1b | Tumor suppressor | [38] |
PCa | LHPP | Phospholysine phosphohistidine inorganic pyrophosphate phosphatase | Tumor suppressor | [66] |
NKX3–1 | NK3 homeobox 1 | Tumor suppressor | [66] | |
miR-495 | microRNA 495 | Tumor suppressor | [67] | |
MOB3B | MOB kinase activator 3B | Tumor suppressor | [67] | |
Bladder cancer | SETD7 | SET domain containing 7 | Tumor suppressor | [65] |
KLF4 | Kruppel like factor 4 | Tumor suppressor | [65] | |
CC | GAS5 | Growth arrest specific 5 | Tumor suppressor | [73] |
Ovarian cancer | BMF | Bcl2 modifying factor | Tumor suppressor | [72] |
Breast cancer | PRSS23 | Serine protease 23 | Tumor suppressor | [71] |
Osteosarcoma | PVT1 | Plasmacytoma variant translocation 1 | Oncogene | [41] |
Melanoma | TP53 | Tumor protein P53 | Tumor suppressor | [75] |
PD-1 | Programmed death 1 | Oncogene | [31] | |
CXCR4 | C-X-C motif chemokine receptor 4 | Oncogene | [31] | |
SOX10 | SRY-Box Transcription Factor 10 | Oncogene | [31] | |
GBM | MYC | MYC proto-oncogene | Oncogene | [76] |
VEGFA | Vascular endothelial growth factor A | Oncogene | [76] | |
LXRA | Liver X receptors A | Tumor suppressor | [77] | |
HIVEP2 | HIVEP Zinc Finger 2 | Tumor suppressor | [77] | |
UBXN1 | UBX domain protein 1 | Tumor suppressor | [78] |