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Fig. 5 | Experimental Hematology & Oncology

Fig. 5

From: Tanshinone IIA attenuates the stemness of breast cancer cells via targeting the miR-125b/STARD13 axis

Fig. 5

MiR-125b/STARD13 enhances MCF-7 cell stemness. A, B Expression levels of stemness markers (ALDH1A1and Oct3/4) were measured in miR-125b overexpressed-MCF-7 cells with overexpressing STARD13 3’UTR or not. C ALDH activity was detected in (A)-depicted cells. D Representative FACS profile of cells described in A were denoted with CD44 + and CD24 − markers. E The capacity of spheroid formation was determined in A-depicted cells. **p < 0. 01 vs. Control, ##p < 0. 01 vs. miR-125b mimics, n = 3. For transfection experiments, control groups were transfected with miR-125b mimics NC

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