Fig. 1
From: Recent advances and challenges of bispecific antibodies in solid tumors
Structure of nature IgG antibody and different formats of bispecific antibodies according to the presence and absence of an Fc region. a Structure of nature IgG molecule. b fragment-based BsAbs contain Diabody, DART, Tandem diabodies, F(ab)2, Dock and Lock. c IgG-like BsAbs mainly include DVD-Ig, Quadromas, mAb2, scFv-Fab IgG, CrossMab, IgG-(scFc)2 and (scFv)4-Fc