Fig. 1From: Molecular subclassification of gastrointestinal cancers based on cancer stem cell traitsCSCs-targeted therapies. Selected anti-CSC drugs targeting developmental pathways and CSC-associated surface markers, which are involved in clinical trials. TGFβ: transforming growth factor; TGFβR: transforming growth factor receptor; LRP: low-densitylipoprotein-related protein; Fz: frizzled; β-cat: β-catenin; NICD: Notch intracellular domain; SMO: smoothenedBack to article page