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Fig. 7 | Experimental Hematology & Oncology

Fig. 7

From: 19-Hydroxybufalin inhibits non-small cell lung cancer cell proliferation and promotes cell apoptosis via the Wnt/β-catenin pathway

Fig. 7

19-HB inhibited NSCLC growth in vivo. Xenograft Balb/c nude mice model was established with NCI-H1299 cells, and the mice were euthanized after completing the treatment. a Tumor volumes of tumor-bearing Bulb/c mice measured on the indicated days. b Tumor size and tumor weights measured. c Serum biochemical indexes to reflect the hepatorenal toxicity of 19-HB. d IHC staining for Ki67 and immunofluorescence staining for TUNEL assay performed in tumor mass, and the positive rate of Ki67 and TUNEL determined on IHC staining afterward (*P < 0.05 vs. control, **P < 0.01 vs. control)

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