Progress in molecular feature of smoldering mantle cell lymphoma

Table 1 2017 WHO classification of mantle cell lymphoma

Mantle cell lymphoma (MCL)
Classical MCL	Mostly SOX11 ( +)
Classical MCL	Unmutated/minimally mutated IGHV
Indolent leukemic non-nodal MCL^a	Mostly SOX11 (−)
Indolent leukemic non-nodal MCL^a	Mutated IGHV
In situ mantle cell neoplasia	New name for in situ MCL, reflecting low clinical risk

^aIndolent leukemic non-nodal MCL with peripheral blood, bone marrow, and sometimes splenic involvement, may become more aggressive

ISSN: 2162-3619