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Table 1 Immunological parameters

From: Whole exome sequencing reveals a novel LRBA mutation and clonal hematopoiesis in a common variable immunodeficiency patient presented with hemophagocytic lymphohistiocytosis

Parameters Measurement at diagnosis Measurement after HSCT (4 months) Normal range
Hemoglobin, g/L 57 110 115–150
Platlet,×109/L 5 133 100–300
Leucocytes, ×109/L 7.5 4.5 4–9
Lymphocytes, ×109/L 0.67 1.8 1.1–3.2
B cells, % 2.8 7.26 5.1–20.3
T cells 95.2 86.74 53.7–80.9
 CD3+CD4+, % 19.9 14.8 19.57–48.02
 CD3+CD8+, % 75.3 71.94 15.8–37.5
 CD4+CD25+FOXP3+,% 0.23 0.49 1.11–2.9
NK cell, % 2.0 6 6.7–30.9
Total T/NK lymphocyte, % 8.96 16.94 17.06–43.35
Cytotoxic T/NK Lymphocyte,% 2.29 3.73 2.86–18.22
Non-Cytotoxic T/NK Lymphocyte,% 6.68 13.21 11.15–35.76
IGG, mg/dL 543 1160 860–1740
IGA, mg/dL 10 79 100–420
IGM, mg/dL 18 123 50–280
C3, mg/dL 78 124 70–140
C4, mg/dL 19 36 10–40
sCd25, pg/ml 22914 5367 < 6400
NK cytotoxicity 22.96% 17.44% ≥ 15.11%