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Table 3 Blood parameters and coagulation factors of influenza patients are compared before and after treatment

From: Platelet-driven coagulopathy in COVID-19 patients: in comparison to seasonal influenza cases

Influenza

Normal range

Before treatment (n = 400)

After treatment (n = 400)

p value

Blood cell counts

    

White blood cells, × 109/L

3.5–9.5

7.3 (5.3–9.9)

6.5 (5.1–8.4)

 < 0.0001

Neutrophils, × 109/L

1.8–6.3

5.4 (3.6–7.7)

4.8 (3.4–6.6)

 < 0.0001

Lymphocytes, × 109/L

1.1–3.2

1.1 (0.8–1.5)

1.3 (0.9–1.8)

0.014

Monocytes, × 109/L

0.1–0.6

0.5 (0.4–0.8)

0.5 (0.4–0.7)

0.002

Red blood cells, × 1012/L

4.3–5.8

4.2 (3.7–4.6)

4.2 (3.7–4.6)

0.212

Hemoglobin, g/L

130–175

127.0 (112.0–137.8)

126.0 (109.0–139.0)

0.988

Hematocrit, %

40–50

37.9 (33.9–41.7)

37.7 (32.8–41.0)

0.257

Platelet, × 109/L

125–350

203.5 (152.3–267.0)

216.0 (166.0–275.5)

 < 0.0001

Mean platelet volume, fL

7.4–12.5

10.7 (9.8–11.6)

10.6 (10.0–11.6)

0.405

Coagulation panel

    

Prothrombin time, s

9–13

12.2 (11.4–14.1)

11.6 (10.9–12.4)

0.560

INR

0.8–1.2

1.0 (1.0–1.2)

1.1 (1.0–1.2)

0.645

aPTT, s

23.3–32.5

27.4 (24.7–31.3)

27.3 (24.9–29.7)

0.027

Thrombin time, s

14–21

17.7 (16.7–19.5)

17.5 (16.4–19.0)

 < 0.0001

Fibrinogen, g/L

2–4

4.2 (3.2–5.3)

3.5 (2.8–4.1)

 < 0.0001

D-dimer, mg/L

 < 0.55

1.1 (0.5–2.5)

0.6 (0.4–1.2)

 < 0.0001