Fig. 2From: Successful salvage therapy for refractory primary cutaneous gamma-delta T-cell lymphoma with a combination of brentuximab vedotin and gemcitabineHistopathology of a skin biopsy. A Panoramic view showing an infiltrate predominantly involving the subcutaneous fat lobules. B Subcutaneous infiltrate with a panniculitis-like pattern, and focal dermal involvement. C CD3 immunostaining showing diffuse CD3 positivity and highlighting the subcutaneous and dermal distribution of the infiltrate. D High-power view of the subcutaneous fat showing an infiltrate of medium to large atypical lymphoid rimming the adipocytes and admixed to histiocytes. E Strong expression of TCR delta by the T cells. F Strong expression of perforin by the T cells. G Partial expression of CD30 by the T cellsBack to article page