Table 1 Comparison of clinical characteristics according to subtype
Patients characteristics | Total | AITL | Other TFH lymphomas | PTCL-NOS | p-value |
|---|---|---|---|---|---|
N (%) | 207 | 111 (53.6) | 29 (14.0) | 67 (32.4) | Â |
Age ≥ 60 years | 99 (47.8) | 66 (61.1) | 15 (51.7) | 27 (40.3) | 0.05 |
Sex | Â | Â | Â | Â | Â |
 Male | 132 (63.8) | 64 (57.7) | 16 (55.2) | 52 (77.6) | 0.01 |
 Female | 75 (36.2) | 47 (42.3) | 13 (44.8) | 15 (22.4) |  |
ECOG | Â | Â | Â | Â | Â |
 0–1 | 182 (87.9) | 95 (85.6) | 24 (82.2) | 63 (94.0) | 0.15 |
 > 2 | 25 (12.1) | 16 (14.4) | 5 (17.2) | 4 (6.0) |  |
Stage | Â | Â | Â | Â | Â |
 I/II | 31 (15.0) | 10 (9.0) | 7 (24.1) | 14 (20.9) | 0.03 |
 III/IV | 176 (85.0) | 101 (91.0) | 22 (75.9) | 53 (79.1) |  |
IPI | Â | Â | Â | Â | Â |
 < 2 | 87 (42.0) | 36 (32.4) | 18 (62.1) | 33 (49.3) | 0.01 |
 ≥ 2 | 120 (58.0) | 75 (67.6) | 11 (37.9) | 34 (50.7) |  |
B-symptom, presence | 80 (38.6) | 56 (50.5) | 8 (27.6) | 16 (23.9) | 0.00 |
Hb < 10 g/dL) | 43 (20.8) | 31 (28.4) | 2 (6.9) | 10 (14.9) | 0.01 |
Hemolytic anemia | 9 (4.3) | 9 (8.1) | 0 | 0 | 0.00 |
Platelet < 100 k | 36 (17.4) | 20 (18.3) | 0 | 16 (23.9) | 0.01 |
Elevated LDH | 119 (57.5) | 71 (65.1) | 10 (34.5) | 38 (56.7) | 0.01 |
Elevated B2M | 107 (51.7) | 65 (58.6) | 7 (24.1) | 35 (52.2) | 0.00 |
IgG ≥ 1600 mg/dL | 44 (21.3) | 33 (29.7) | 2 (6.9) | 9 (13.4) | 0.00 |
IgA ≥ 400 mg/dL | 23 (11.1) | 16 (14.4) | 2 (6.9) | 5 (7.5) | 0.00 |
IgM ≥ 230 mg/dL | 30 (14.5) | 29 (26.1) | 1 (3.4) | 0 (0.0) | 0.00 |
Serum EBV, positive | 62 (30.0) | 45 (40.5) | 9 (31.0) | 8 (11.9) | 0.00 |
Splenomegaly | 83 (40.1) | 53 (47.7) | 6 (20.7) | 24 (35.8) | 0.02 |
BM involvement | 73 (35.3) | 46 (41.4) | 9 (31.0) | 18 (27.7) | 0.17 |