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Table 2 Univariate and multivariate analyses of factors associated with survival and recurrence

From: PCSK9 promotes tumor growth by inhibiting tumor cell apoptosis in hepatocellular carcinoma

Factor Overall survival Disease-free survival
  Univariate Multivariate Univariate Multivariate
p Hazard ratio 95% CI p p Hazard Ratio 95% CI p
Age (years)
 ≤ 50 vs > 50
0.664    NA 0.381    NA
Gender
 Female vs Male
0.982    NA 0.972    NA
AFP (ng/ml)
 > 20 vs ≤ 20
0.001 2.94 1.644
−5.258
0.000 0.005 2.292 1.410
−3.724
0.001
Number of tumors
 Multiple vs single
0.079    NA 0.037 1.668 1.021
−2.723
0.041
Tumor size (cm)
 > 5 vs ≤ 5
0.000 2.572 1.460
−4.529
0.001 0.002 1.812 1.115
−2.946
0.017
Tumor cell
differentiation
 III–IV vs I–II
0.008 1.699 0.975
–2.961
0.061 0.248    NA
Microvascular invasion
 Yes vs No
0.018 1.246 0.690
–2.251
0.465 0.057    NA
PCSK9 0.035 1.788 1.003
–3.185
0.049 0.007 1.956 1.199
−3.192
0.007
 High vs Low
  1. NA: not applicable