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Fig. 5 | Experimental Hematology & Oncology

Fig. 5

From: Profiling of somatic mutations and fusion genes in acute myeloid leukemia patients with FLT3-ITD or FLT3-TKD mutation at diagnosis reveals distinct evolutionary patterns

Fig. 5

Molecular heterogeneity of AML exemplified by mutational and fusion genes profiling in FLT3-AML. Each spoke radiating from the central FLT3-ITD or FLT3-TKD hub represents the molecular pattern of a single patient. Cooperating mutations are grouped into three tiers according to the function and color-coded according to the figure key, and white space indicates no mutation or fusion. Overall, based on molecular combination, patients are segregated into different subgroups

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