Fig. 5From: Profiling of somatic mutations and fusion genes in acute myeloid leukemia patients with FLT3-ITD or FLT3-TKD mutation at diagnosis reveals distinct evolutionary patternsMolecular heterogeneity of AML exemplified by mutational and fusion genes profiling in FLT3-AML. Each spoke radiating from the central FLT3-ITD or FLT3-TKD hub represents the molecular pattern of a single patient. Cooperating mutations are grouped into three tiers according to the function and color-coded according to the figure key, and white space indicates no mutation or fusion. Overall, based on molecular combination, patients are segregated into different subgroupsBack to article page