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Table 5. Coagulation abnormalities/clinical prognostic factors and VTE

From: COVID-19-associated coagulopathy: thromboembolism prophylaxis and poor prognosis in ICU

Prognostic factors VTE non-VTE P value
No. % No. %
Temperaturemax (°C) 0.780
 ≥39 12 46.15 4 15.38  
 <39 7 26.92 3 11.54  
Duration of Low BP (h) 0.171
 0 6 23.08 5 19.23  
 <72 2 7.69 0 0.00  
 ≥72 11 42.31 2 7.69  
Blood transfusion (ml) 0.184
 0 6 23.08 5 19.23  
 ≤800 8 30.77 1 3.85  
 >800 5 19.23 1 3.85  
Lymphocyte 0.952
 ≥1.0 × 109/L 3 11.54 1 3.85  
 <1.0 × 109/L 16 61.54 6 23.08  
Platelet count 0.143
 ≥150 × 109/L 14 53.85 3 11.54  
 <150 × 109/L 5 19.23 4 15.38  
SIC score 0.258
 <4 17 65.38 5 19.23  
 ≥4 2 7.69 2 7.69  
DIC score 0.269
 <5 12 46.15 6 23.08  
 ≥5 7 26.92 1 3.85  
Overt DIC 0.124
 Yes 9 34.62 1 3.85  
 No 10 38.46 6 23.08  
Prolongation of PT (s)  
 >3 0 0.00 0   
 ≤3 19 73.08 7 26.92  
Prolongation of aPTT (s) 0.536
 >10 1 3.85 0   
 ≤10 18 69.23 7 26.92  
 Fbg (g/L) 0.423
 1.5–4 4 15.38 2 7.69  
 >4 9 34.62 10 38.46  
 <1.5 0 0.00 1 3.85  
D-dimer (mg/L) 0.510
 ≤0.5 2 7.69 0   
 >0.5 and ≤2 5 19.23 5 19.23  
 >2 and <5 2 7.69 3 11.54  
 >5 4 15.38 5 19.23  
Antithrombin (%) 0.627
 ≥80 11 42.31 4 15.38  
 <80 5 19.23 1 3.85  
Serum calcium levels (mmol/L)  
 ≥1.8 19 73.08 7 26.92  
 <1.8 0 0.00 0   
VTE prophylaxis 0.78
 Yes 12 46.15 4 15.38  
 No 7 26.92 3 11.54  
  1. BP blood pressure, SIC sepsis-induced coagulopathy, DIC disseminated intravascular coagulation, PT prothrombin time, aPTT activated partial thromboplastin time,Fbg fibrinogen, VTE venous thromboembolism
  2. Blood transfusion: red blood cells, platelet or fresh-frozen plasma