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Table 5. Coagulation abnormalities/clinical prognostic factors and VTE

From: COVID-19-associated coagulopathy: thromboembolism prophylaxis and poor prognosis in ICU

Prognostic factors

VTE

non-VTE

P value

No.

%

No.

%

Temperaturemax (°C)

0.780

 ≥39

12

46.15

4

15.38

 

 <39

7

26.92

3

11.54

 

Duration of Low BP (h)

0.171

 0

6

23.08

5

19.23

 

 <72

2

7.69

0

0.00

 

 ≥72

11

42.31

2

7.69

 

Blood transfusion (ml)

0.184

 0

6

23.08

5

19.23

 

 ≤800

8

30.77

1

3.85

 

 >800

5

19.23

1

3.85

 

Lymphocyte

0.952

 ≥1.0 × 109/L

3

11.54

1

3.85

 

 <1.0 × 109/L

16

61.54

6

23.08

 

Platelet count

0.143

 ≥150 × 109/L

14

53.85

3

11.54

 

 <150 × 109/L

5

19.23

4

15.38

 

SIC score

0.258

 <4

17

65.38

5

19.23

 

 ≥4

2

7.69

2

7.69

 

DIC score

0.269

 <5

12

46.15

6

23.08

 

 ≥5

7

26.92

1

3.85

 

Overt DIC

0.124

 Yes

9

34.62

1

3.85

 

 No

10

38.46

6

23.08

 

Prolongation of PT (s)

 

 >3

0

0.00

0

  

 ≤3

19

73.08

7

26.92

 

Prolongation of aPTT (s)

0.536

 >10

1

3.85

0

  

 ≤10

18

69.23

7

26.92

 

 Fbg (g/L)

0.423

 1.5–4

4

15.38

2

7.69

 

 >4

9

34.62

10

38.46

 

 <1.5

0

0.00

1

3.85

 

D-dimer (mg/L)

0.510

 ≤0.5

2

7.69

0

  

 >0.5 and ≤2

5

19.23

5

19.23

 

 >2 and <5

2

7.69

3

11.54

 

 >5

4

15.38

5

19.23

 

Antithrombin (%)

0.627

 ≥80

11

42.31

4

15.38

 

 <80

5

19.23

1

3.85

 

Serum calcium levels (mmol/L)

 

 ≥1.8

19

73.08

7

26.92

 

 <1.8

0

0.00

0

  

VTE prophylaxis

0.78

 Yes

12

46.15

4

15.38

 

 No

7

26.92

3

11.54

 
  1. BP blood pressure, SIC sepsis-induced coagulopathy, DIC disseminated intravascular coagulation, PT prothrombin time, aPTT activated partial thromboplastin time,Fbg fibrinogen, VTE venous thromboembolism
  2. Blood transfusion: red blood cells, platelet or fresh-frozen plasma