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Table 1. Scoring systems used to analyse associations of coagulation abnormalities and mortality

From: COVID-19-associated coagulopathy: thromboembolism prophylaxis and poor prognosis in ICU

A. ISTH SIC scoring system

  

Item

Score

Range

Platelet count (×109/L)

1

100-150

 

2

<100

PT-INR

1

1.2-1.4

 

2

>1.4

SOFA score

1

1

 

2

≥2

B. Chinese DIC scoring system

 

Item

Score

Primary disease leading to DIC

2

Clinical manifestations

 Severe bleeding

1

 Shock

1

 Extensive cutaneous and mucosal embolism, or focal ischemic necrosis, or unexplained organ failure

1

Platelet count (×109/L)

 Non-hematology malignancy

  ≥100

0

  80–< 100

1

  <80

2

  Decrease > 50% within 24h

1

 Hematology malignancy

  < 50

1

  Decrease > 50% within 24h

1

D-dimer (mg/L)

 < 5

0

 5–< 9

2

 ≥9

3

PT and aPTT (sec)

 Prolongation of PT< 3 or aPTT< 10

0

 Prolongation of PT≥3 or aPTT≥10

1

 Prolongation of PT≥6

2

Fbg (g/L)

 ≥1.0

0

  < 1.0

1

  1. ISTH International Society on Thrombosis and Haemostasis, SIC sepsis-induced coagulopathy, PT-INR prothrombin time–international normalised ratio, SOFA Sequential Organ Failure Assessment (SOFA score is the sum of four items: respiratory SOFA, cardiovascular SOFA, hepatic SOFA, and renal SOFA). DIC disseminated intravascular coagulation, PT prothrombin time, aPTT activated partial thromboplastin time, Fbg fibrinogen