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Table 1 Primary indices’ rates of hematologic malignancies in 1990 and 2017 at the global level

From: A global, regional, and national survey on burden and Quality of Care Index (QCI) of hematologic malignancies; global burden of disease systematic analysis 1990–2017

Measure Metric Hodgkin lymphoma Non-Hodgkin lymphoma Multiple myeloma Leukemia
1990 (95% UI) 2017 (95% UI) Statistically Significant? 1990 (95% UI) 2017 (95% UI) Statistically Significant? 1990 (95% UI) 2017 (95% UI) Statistically Significant? 1990 (95% UI) 2017 (95% UI) Statistically Significant?
Prevalence Number 378,758 (286,249 to 414,343) 657,094 (568,931 to 780,837) Yes 857,555 (828,438 to 895,762) 2,371,891 (2,324,951 to 2,418,127) Yes 147,856 (132,552 to 171,190) 449,310 (414,568 to 520,850) Yes 1,528,800 (1,272,203 to 1,797,889) 2,432,388 (2,190,332 to 2,591,602) Yes
Rate 7.2 (5.4 to 7.8) 8.3 (7.2 to 9.9) No 18.9 (18.4 to 19.6) 29.7 (29.1 to 30.3) Yes 3.5 (3.2 to 4.1) 5.5 (5.1 to 6.4) Yes 30.2 (25.9 to 34.5) 32.4 (29 to 34.6) No
Incidence Number 72,937 (55,801 to 79,370) 101,133 (87,968 to 118,746) Yes 206,863 (199,638 to 216,794) 487,964 (478,850 to 496,904) Yes 65,487 (60,070 to 76,525) 152,746 (140,564 to 172,662) Yes 354,471 (308,198 to 399,303) 518,485 (472,240 to 548,018) Yes
Rate 1.4 (1.1 to 1.6) 1.3 (1.1 to 1.5) No 4.7 (4.6 to 4.9) 6.2 (6.1 to 6.3) Yes 1.6 (1.5 to 1.9) 1.9 (1.8 to 2.2) No 7.4 (6.6 to 8.2) 6.8 (6.1 to 7.2) No
Death Number 35,946 (27,329 to 39,412) 32,560 (27,644 to 38,086) No 134,689 (129,673 to 142,079) 248,636 (243,475 to 253,064) Yes 52,277 (48,480 to 61,265) 107,114 (98,521 to 118,911) Yes 264,888 (234,391 to 292,591) 347,583 (317,256 to 364,877) Yes
Rate 0.8 (0.6 to 0.8) 0.4 (0.4 to 0.5) Yes 3.2 (3.1 to 3.3) 3.2 (3.1 to 3.2) No 1.3 (1.3 to 1.6) 1.4 (1.3 to 1.5) No 5.8 (5.3 to 6.3) 4.5 (4.1 to 4.7) Yes
YLLs Number 1,625,133 (1,205,998 to 1,807,341) 1,327,631 (1,110,146 to 1,567,680) No 4,497,053 (4,162,545 to 4,943,867) 6828,795 (6,611,841 to 7,019,991) Yes 1,183,624 (1,095,061 to 1,349,698) 2,234,726 (2,091,390 to 2,493,151) Yes 11,806,875 (9,724,465 to 13,876,452) 11,712,000 (10,531,416 to 12,523,323) No
Rate 30.9 (23.1 to 34) 17.1 (14.3 to 20.2) Yes 92.9 (87.2 to 100.7) 86.8 (84 to 89.5) No 28 (26 to 32.3) 27.7 (25.9 to 30.8) No 221.9 (186.7 to 255.8) 153.4 (137.9 to 164.5) Yes
YLDs Number 32,336 (21,127 to 44,675) 50,534 (35,126 to 69,346) No 76,792 (55,686 to 100,940) 193,118 (140,222 to 254,172) Yes 32,531 (22,814 to 42,284) 90,764 (64,211 to 118,424) Yes 164,720 (116,396 to 222,554) 263,348 (191,210 to 342,035) No
Rate 0.6 (0.4 to 0.9) 0.6 (0.4 to 0.9) No 1.7 (1.3 to 2.3) 2.4 (1.8 to 3.2) No 0.8 (0.5 to 1) 1.1 (0.8 to 1.5) No 3.5 (2.5 to 4.6) 3.4 (2.5 to 4.5) No
DALYs Number 1,657,469 (1,228,330 to 1,843,223) 1,378,166 (1,155,059 to 1,624,392) No 4,573,845 (4,236,062 to 5,018,937) 7,021,913 (6,794,727 to 7,232,477) Yes 1,216,155 (1,127,669 to 1,388,918) 2,325,490 (2,176,068 to 2,606,756) Yes 11,971,595 (9,868,922 to 14,047,583) 11,975,348 (10,749,148 to 12,793,575) No
Rate 31.5 (23.6 to 34.7) 17.8 (14.9 to 20.9) Yes 94.6 (88.9 to 102.5) 89.3 (86.1 to 92.2) No 28.8 (26.7 to 33.3) 28.8 (26.9 to 32.2) No 225.4 (190.2 to 259.3) 156.8 (140.8 to 168.1) Yes
  1. Data are derived from GBD 2017. Both age-standardized and crude rates (with 95% uncertainty intervals) of primary indices are represented in the table. DALYs disability-adjusted life-years, GBD Global Burden of Disease, YLDs years lived with disability, YLLs years of life lost
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