The degree of microsatellite instability predicts response to PD-1 blockade immunotherapy in mismatch repair-deficient/microsatellite instability-high colorectal cancers

Table 2 Treatment response and ORR of patients stratified by the number of instability loci

Number of instability loci	Number of cases	CR^*	PR	SD	PD	ORR
0	3	0	0	2	1	0
1	5	0	0	2	3	0
2	9	2	4	1	2	0.67
3	9	5	2	1	1	0.78
4	4	2	1	1	0	0.75
5	3	1	2	0	0	1

CR complete response, PR partial response, SD stable disease, PD progressive disease, ORR objective response rate
^*For patients who underwent surgical resection and had a pathological confirmed complete response, treatment response was recorded as CR

ISSN: 2162-3619