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Table 2 Clinical study of antitumor drugs targeting cAMP–PKA pathway (from clinicaltrials.gov)

From: Complex roles of cAMP–PKA–CREB signaling in cancer

Identifier

Title

Cancer type

Locations

NCT00004902

Tocladesine in treating patients with recurrent or refractory multiple myeloma

Multiple myeloma and plasma cell tumor

Robert H. Lurie Comprehensive Cancer Center, Northwestern University

Chicago, Illinois, United States

NCT00021268

Tocladesine in treating patients with recurrent or progressive metastatic colorectal cancer

Colorectal cancer

Jonsson Comprehensive Cancer Center, UCLA

Los Angeles, California, United States

NCT00004864

Docetaxel and GEM 231 in treating patients with recurrent or refractory solid tumors

Unspecified adult solid tumor

Albert Einstein Comprehensive Cancer Center

Bronx, New York, United States

NCT00004863

Paclitaxel and GEM 231 in treating patients with recurrent or refractory solid tumors

Unspecified adult solid tumor

Albert Einstein Comprehensive Cancer Center

Bronx, New York, United States