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Table 2 The death cases and ASDR of CML in 1990 and 2017, and its temporal trends from 1990 to 2017

From: Trends in disease burden of chronic myeloid leukemia at the global, regional, and national levels: a population-based epidemiologic study

  Death cases no. *102 (95% UI) Change in absolute number (%) ASDR per 100,000 No. (95% UI) 1990–2017 EAPCs No. (95% CI)
1990 2017 1990 2017
Overall 241.98 (226.32–261.08) 240.54 (222.33–260.72) − 0.59 0.59 (0.56–0.63) 0.31 (0.28–0.33) − 2.76 (− 2.89 to − 2.63)
Sex
 Male 125.44 (116.35–134.96) 129.15 (116.44–140.91) 2.96 0.69 (0.65–0.74) 0.36 (0.33–0.39) − 2.66 (− 2.78 to − 2.53)
 Female 116.54 (104.35–134.27) 111.39 (96.83–127.32) − 4.42 0.53 (0.48–0.6) 0.26 (0.23–0.3) − 2.9 (− 3.03 to − 2.76)
Socio-demographic index
 High SDI 115.87 (112.65–119.04) 70.66 (67.96–73.85) − 39.02 0.92 (0.9–0.95) 0.31 (0.3–0.32) − 4.58 (− 4.8 to − 4.36)
 High-middle SDI 39.35 (35.19–43.45) 33.92 (31.8–37.07) − 13.79 0.4 (0.36–0.44) 0.2 (0.18–0.21) − 3.04 (− 3.27 to − 2.8)
 Middle SDI 30.18 (27.14–35.29) 45.79 (39.63–49.07) 51.72 0.29 (0.26–0.33) 0.21 (0.18–0.23) − 1.29 (− 1.39 to − 1.19)
 Low-middle SDI 27.62 (24.17–34.96) 45.12 (39.06–52.46) 63.38 0.44 (0.39–0.56) 0.37 (0.32–0.43) − 0.71 (− 0.82 to − 0.6)
 Low SDI 28.54 (23.03–35.73) 44.67 (37.71–50.65) 56.53 0.77 (0.64–0.95) 0.6 (0.5–0.68) − 1.03 (− 1.07 to − 0.98)
Region
 Andean Latin America 0.7 (0.59–0.81) 1.46 (1.19–1.64) 107.23 0.29 (0.25–0.33) 0.26 (0.21–0.29) − 0.29 (− 0.42 to − 0.15)
 Australasia 2.86 (2.74–3) 2.13 (1.89–2.43) − 25.51 1.21 (1.15–1.26) 0.44 (0.39–0.5) − 4.6 (− 4.88 to − 4.32)
 Caribbean 2.23 (2.05–2.44) 2.45 (2.21–2.73) 9.81 0.81 (0.75–0.89) 0.48 (0.44–0.54) − 2.04 (− 2.2 to − 1.87)
 Central Asia 2.01 (1.72–2.29) 1.98 (1.75–2.2) − 1.78 0.37 (0.32–0.43) 0.25 (0.22–0.27) − 1.67 (− 1.86 to − 1.47)
 Central Europe 9.76 (9.26–10.31) 6.42 (6.06–6.83) − 34.21 0.67 (0.63–0.7) 0.31 (0.29–0.33) − 3.07 (− 3.29 to − 2.86)
 Central Latin America 5.57 (5.36–5.82) 8.55 (8.06–9.03) 53.44 0.57 (0.55–0.6) 0.36 (0.34–0.38) − 2.02 (− 2.22 to − 1.83)
 Central Sub-Saharan Africa 1.28 (0.87–1.62) 3.02 (2.21–3.75) 135.58 0.49 (0.34–0.61) 0.54 (0.39–0.67) 0.55 (0.45 to 0.65)
 East Asia 14.93 (11.9–18.59) 11.79 (9.94–13.91) − 21.05 0.14 (0.11–0.17) 0.06 (0.05–0.07) − 3.56 (− 3.81 to − 3.3)
 Eastern Europe 14.8 (13.44–16.76) 12.37 (11.71–13.09) − 16.39 0.53 (0.48–0.6) 0.38 (0.36–0.4) − 1.59 (− 1.95 to − 1.22)
 Eastern Sub-Saharan Africa 9.74 (7.34–13.08) 13.98 (10.71–16.95) 43.43 1.06 (0.83–1.41) 0.77 (0.59–0.94) − 1.4 (− 1.5 to − 1.3)
 High-income Asia Pacific 10.33 (9.96–10.73) 6.01 (5.64–6.4) − 41.8 0.52 (0.5–0.54) 0.14 (0.13–0.15) − 5.12 (− 5.31 to − 4.94)
 High-income North America 28.39 (27.68–29.2) 15.6 (14.97–16.43) − 45.05 0.81 (0.79–0.83) 0.26 (0.25–0.27) − 5.06 (− 5.49 to − 4.62)
 North Africa and Middle East 9.66 (7.03–11.7) 12.32 (10.13–14.35) 27.53 0.51 (0.37–0.62) 0.28 (0.23–0.32) − 2.26 (− 2.34 to − 2.19)
 Oceania 0.26 (0.2–0.34) 0.41 (0.31–0.56) 56.59 0.66 (0.52–0.84) 0.47 (0.37–0.62) − 1.27 (− 1.33 to − 1.21)
 South Asia 38.65 (32.95–47.99) 66.6 (57.12–76.5) 72.32 0.6 (0.51–0.76) 0.49 (0.43–0.57) − 0.8 (− 0.9 to − 0.71)
 Southeast Asia 9.92 (8.24–14.64) 16.51 (13.01–19.91) 66.46 0.34 (0.29–0.5) 0.28 (0.22–0.33) − 0.74 (− 0.88 to − 0.61)
 Southern Latin America 3.21 (2.96–3.47) 2.29 (2.05–2.52) − 28.84 0.69 (0.63–0.74) 0.28 (0.25–0.31) − 3.87 (− 4.28 to − 3.46)
 Southern Sub-Saharan Africa 0.27 (0.2–0.33) 0.37 (0.28–0.46) 40.37 0.08 (0.06–0.1) 0.06 (0.05–0.08) − 0.87 (− 1.44 to − 0.3)
 Tropical Latin America 5.8 (5.58–6.04) 5.97 (5.73–6.29) 2.84 0.56 (0.54–0.59) 0.26 (0.25–0.28) − 3.23 (− 3.59 to − 2.87)
 Western Europe 67.54 (64.82–70.15) 42.45 (40.25–44.87) − 37.16 1.17 (1.13–1.21) 0.44 (0.41–0.46) − 4.16 (− 4.4 to − 3.92)
 Western Sub-Saharan Africa 4.05 (3.17–5.07) 7.87 (6.28–9.9) 94.46 0.4 (0.31–0.5) 0.37 (0.3–0.47) − 0.21 (− 0.23 to − 0.19)
  1. ASDR age-standardized death rate, CI confidence interval, EAPCs estimated annual percentage changes, UI uncertainty interval