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Table 2 The death cases and ASDR of CML in 1990 and 2017, and its temporal trends from 1990 to 2017

From: Trends in disease burden of chronic myeloid leukemia at the global, regional, and national levels: a population-based epidemiologic study

 

Death cases no. *102 (95% UI)

Change in absolute number (%)

ASDR per 100,000 No. (95% UI)

1990–2017 EAPCs No. (95% CI)

1990

2017

1990

2017

Overall

241.98 (226.32–261.08)

240.54 (222.33–260.72)

− 0.59

0.59 (0.56–0.63)

0.31 (0.28–0.33)

− 2.76 (− 2.89 to − 2.63)

Sex

 Male

125.44 (116.35–134.96)

129.15 (116.44–140.91)

2.96

0.69 (0.65–0.74)

0.36 (0.33–0.39)

− 2.66 (− 2.78 to − 2.53)

 Female

116.54 (104.35–134.27)

111.39 (96.83–127.32)

− 4.42

0.53 (0.48–0.6)

0.26 (0.23–0.3)

− 2.9 (− 3.03 to − 2.76)

Socio-demographic index

 High SDI

115.87 (112.65–119.04)

70.66 (67.96–73.85)

− 39.02

0.92 (0.9–0.95)

0.31 (0.3–0.32)

− 4.58 (− 4.8 to − 4.36)

 High-middle SDI

39.35 (35.19–43.45)

33.92 (31.8–37.07)

− 13.79

0.4 (0.36–0.44)

0.2 (0.18–0.21)

− 3.04 (− 3.27 to − 2.8)

 Middle SDI

30.18 (27.14–35.29)

45.79 (39.63–49.07)

51.72

0.29 (0.26–0.33)

0.21 (0.18–0.23)

− 1.29 (− 1.39 to − 1.19)

 Low-middle SDI

27.62 (24.17–34.96)

45.12 (39.06–52.46)

63.38

0.44 (0.39–0.56)

0.37 (0.32–0.43)

− 0.71 (− 0.82 to − 0.6)

 Low SDI

28.54 (23.03–35.73)

44.67 (37.71–50.65)

56.53

0.77 (0.64–0.95)

0.6 (0.5–0.68)

− 1.03 (− 1.07 to − 0.98)

Region

 Andean Latin America

0.7 (0.59–0.81)

1.46 (1.19–1.64)

107.23

0.29 (0.25–0.33)

0.26 (0.21–0.29)

− 0.29 (− 0.42 to − 0.15)

 Australasia

2.86 (2.74–3)

2.13 (1.89–2.43)

− 25.51

1.21 (1.15–1.26)

0.44 (0.39–0.5)

− 4.6 (− 4.88 to − 4.32)

 Caribbean

2.23 (2.05–2.44)

2.45 (2.21–2.73)

9.81

0.81 (0.75–0.89)

0.48 (0.44–0.54)

− 2.04 (− 2.2 to − 1.87)

 Central Asia

2.01 (1.72–2.29)

1.98 (1.75–2.2)

− 1.78

0.37 (0.32–0.43)

0.25 (0.22–0.27)

− 1.67 (− 1.86 to − 1.47)

 Central Europe

9.76 (9.26–10.31)

6.42 (6.06–6.83)

− 34.21

0.67 (0.63–0.7)

0.31 (0.29–0.33)

− 3.07 (− 3.29 to − 2.86)

 Central Latin America

5.57 (5.36–5.82)

8.55 (8.06–9.03)

53.44

0.57 (0.55–0.6)

0.36 (0.34–0.38)

− 2.02 (− 2.22 to − 1.83)

 Central Sub-Saharan Africa

1.28 (0.87–1.62)

3.02 (2.21–3.75)

135.58

0.49 (0.34–0.61)

0.54 (0.39–0.67)

0.55 (0.45 to 0.65)

 East Asia

14.93 (11.9–18.59)

11.79 (9.94–13.91)

− 21.05

0.14 (0.11–0.17)

0.06 (0.05–0.07)

− 3.56 (− 3.81 to − 3.3)

 Eastern Europe

14.8 (13.44–16.76)

12.37 (11.71–13.09)

− 16.39

0.53 (0.48–0.6)

0.38 (0.36–0.4)

− 1.59 (− 1.95 to − 1.22)

 Eastern Sub-Saharan Africa

9.74 (7.34–13.08)

13.98 (10.71–16.95)

43.43

1.06 (0.83–1.41)

0.77 (0.59–0.94)

− 1.4 (− 1.5 to − 1.3)

 High-income Asia Pacific

10.33 (9.96–10.73)

6.01 (5.64–6.4)

− 41.8

0.52 (0.5–0.54)

0.14 (0.13–0.15)

− 5.12 (− 5.31 to − 4.94)

 High-income North America

28.39 (27.68–29.2)

15.6 (14.97–16.43)

− 45.05

0.81 (0.79–0.83)

0.26 (0.25–0.27)

− 5.06 (− 5.49 to − 4.62)

 North Africa and Middle East

9.66 (7.03–11.7)

12.32 (10.13–14.35)

27.53

0.51 (0.37–0.62)

0.28 (0.23–0.32)

− 2.26 (− 2.34 to − 2.19)

 Oceania

0.26 (0.2–0.34)

0.41 (0.31–0.56)

56.59

0.66 (0.52–0.84)

0.47 (0.37–0.62)

− 1.27 (− 1.33 to − 1.21)

 South Asia

38.65 (32.95–47.99)

66.6 (57.12–76.5)

72.32

0.6 (0.51–0.76)

0.49 (0.43–0.57)

− 0.8 (− 0.9 to − 0.71)

 Southeast Asia

9.92 (8.24–14.64)

16.51 (13.01–19.91)

66.46

0.34 (0.29–0.5)

0.28 (0.22–0.33)

− 0.74 (− 0.88 to − 0.61)

 Southern Latin America

3.21 (2.96–3.47)

2.29 (2.05–2.52)

− 28.84

0.69 (0.63–0.74)

0.28 (0.25–0.31)

− 3.87 (− 4.28 to − 3.46)

 Southern Sub-Saharan Africa

0.27 (0.2–0.33)

0.37 (0.28–0.46)

40.37

0.08 (0.06–0.1)

0.06 (0.05–0.08)

− 0.87 (− 1.44 to − 0.3)

 Tropical Latin America

5.8 (5.58–6.04)

5.97 (5.73–6.29)

2.84

0.56 (0.54–0.59)

0.26 (0.25–0.28)

− 3.23 (− 3.59 to − 2.87)

 Western Europe

67.54 (64.82–70.15)

42.45 (40.25–44.87)

− 37.16

1.17 (1.13–1.21)

0.44 (0.41–0.46)

− 4.16 (− 4.4 to − 3.92)

 Western Sub-Saharan Africa

4.05 (3.17–5.07)

7.87 (6.28–9.9)

94.46

0.4 (0.31–0.5)

0.37 (0.3–0.47)

− 0.21 (− 0.23 to − 0.19)

  1. ASDR age-standardized death rate, CI confidence interval, EAPCs estimated annual percentage changes, UI uncertainty interval