Table 1 The incidence cases and ASIR of CML in 1990 and 2017, and its temporal trends from 1990 to 2017
|  | Incident cases no. *102 (95% UI) | Change in absolute number (%) | ASIR per 100,000 No. (95% UI) | 1990–2017 EAPCs No. (95% CI) | ||
|---|---|---|---|---|---|---|
1990 | 2017 | 1990 | 2017 | |||
Overall | 317.52 (295.9–340.66) | 341.79 (315.16–367.14) | 7.64 | 0.75 (0.71–0.8) | 0.43 (0.4–0.46) | -2.4 (− 2.53 to − 2.26) |
Sex | ||||||
 Male | 165.57 (153.46–177.23) | 191.45 (173.2–208.22) | 15.64 | 0.86 (0.8–0.92) | 0.52 (0.47–0.57) | − 2.17 (− 2.29 to − 2.05) |
 Female | 151.96 (135.82–171.91) | 150.33 (130.96–170.43) | − 1.07 | 0.67 (0.61–0.75) | 0.36 (0.31–0.41) | − 2.7 (− 2.85 to − 2.55) |
Socio- demographic index | ||||||
 High SDI | 163.42 (157.15–169.51) | 106.4 (100.95–112.18) | − 34.89 | 1.34 (1.29–1.38) | 0.53 (0.51–0.56) | − 4 (− 4.23 to − 3.78) |
 High-middle SDI | 49.58 (43.76–55.26) | 57.35 (52.42–62.39) | 15.69 | 0.49 (0.43–0.54) | 0.33 (0.3–0.36) | − 1.77 (− 1.95 to − 1.6) |
 Middle SDI | 38.31 (34.17–44.49) | 67.71 (58.04–72.69) | 76.73 | 0.33 (0.3–0.39) | 0.3 (0.26–0.32) | − 0.56 (− 0.66 to − 0.45) |
 Low-middle SDI | 32.8 (28.42–41.59) | 56.67 (49.19–65.98) | 72.79 | 0.48 (0.42–0.61) | 0.43 (0.37–0.5) | − 0.48 (− 0.6 to − 0.36) |
 Low SDI | 32.8 (25.9–41.69) | 52.85 (44.44–59.95) | 61.14 | 0.81 (0.67–1.01) | 0.65 (0.55–0.74) | − 0.93 (− 0.97 to − 0.88) |
Region | ||||||
 Andean Latin America | 0.87 (0.73–1) | 2.08 (1.69–2.39) | 138.66 | 0.34 (0.28–0.38) | 0.36 (0.29–0.42) | 0.46 (0.32–0.6) |
 Australasia | 3.87 (3.36–4.44) | 3.58 (2.95–4.32) | − 7.43 | 1.64 (1.43–1.87) | 0.83 (0.68–1) | − 3.35 (− 3.66 to − 3.03) |
 Caribbean | 2.64 (2.41–2.91) | 3.07 (2.73–3.48) | 16.28 | 0.93 (0.85–1.02) | 0.61 (0.54–0.69) | − 1.7 (− 1.84 to − 1.57) |
 Central Asia | 2.52 (2.16–2.88) | 2.74 (2.41–3.07) | 8.73 | 0.45 (0.39–0.51) | 0.32 (0.28–0.36) | − 1.34 (− 1.57 to − 1.11) |
 Central Europe | 11.11 (10.48–11.77) | 6.82 (6.42–7.27) | − 38.62 | 0.77 (0.73–0.82) | 0.37 (0.35–0.4) | − 2.87 (− 3.14 to − 2.6) |
 Central Latin America | 6.98 (6.69–7.4) | 11.96 (11.22–12.85) | 71.35 | 0.66 (0.64–0.7) | 0.49 (0.46–0.53) | − 1.47 (− 1.7 to − 1.23) |
 Central Sub-Saharan Africa | 1.49 (0.99–1.92) | 3.61 (2.64–4.51) | 142.15 | 0.51 (0.35–0.64) | 0.57 (0.42–0.72) | 0.58 (0.47 to 0.69) |
 East Asia | 22.64 (17.43–28.02) | 32.71 (27.97–37.64) | 44.49 | 0.19 (0.16–0.24) | 0.17 (0.15–0.19) | − 0.99 (− 1.21 to − 0.76) |
 Eastern Europe | 18.01 (15.98–20.72) | 18.51 (16.46–20.67) | 2.77 | 0.66 (0.59–0.75) | 0.61 (0.54–0.69) | − 0.55 (− 0.86 to − 0.25) |
 Eastern Sub-Saharan Africa | 11.1 (8.15–15.09) | 16.39 (12.56–19.89) | 47.6 | 1.11 (0.86–1.49) | 0.81 (0.63–0.98) | − 1.41 (− 1.51 to − 1.31) |
 High-income Asia Pacific | 17.08 (15.68–18.57) | 12.81 (11.33–14.46) | − 25.03 | 0.87 (0.79–0.94) | 0.39 (0.34–0.44) | − 3.2 (− 3.37 to − 3.02) |
High-income North America | 34.1 (32.98–35.37) | 20.55 (19.44–21.81) | − 39.75 | 1.02 (0.98–1.06) | 0.4 (0.37–0.43) | − 4.28 (− 4.66 to − 3.9) |
 North Africa and Middle East | 11.85 (8.69–14.29) | 18.32 (15.18–21.5) | 54.62 | 0.57 (0.42–0.69) | 0.38 (0.32–0.44) | − 1.59 (− 1.67 to − 1.52) |
 Oceania | 0.33 (0.25–0.44) | 0.55 (0.41–0.78) | 67.15 | 0.78 (0.6–1) | 0.59 (0.45–0.79) | − 1.06 (− 1.09 to − 1.03) |
 South Asia | 44.97 (38.05–55.49) | 80.44 (69.27–91.61) | 78.87 | 0.64 (0.55–0.79) | 0.56 (0.48–0.63) | − 0.58 (− 0.68 to − 0.48) |
 Southeast Asia | 12.41 (10.18–17.69) | 25.17 (19.85–29.4) | 102.88 | 0.39 (0.33–0.57) | 0.4 (0.31–0.46) | 0.05 (− 0.08 to 0.17) |
 Southern Latin America | 3.77 (3.47–4.09) | 3 (2.69–3.35) | − 20.44 | 0.8 (0.73–0.87) | 0.38 (0.34–0.43) | − 3.29 (− 3.71 to − 2.88) |
 Southern Sub-Saharan Africa | 0.33 (0.25–0.42) | 0.48 (0.36–0.6) | 46.63 | 0.1 (0.07–0.12) | 0.08 (0.06–0.09) | − 0.77 (− 1.37 to − 0.16) |
 Tropical Latin America | 7.2 (6.88–7.55) | 7.65 (7.26–8.15) | 6.36 | 0.65 (0.62–0.68) | 0.33 (0.31–0.35) | − 2.93 (− 3.34 to − 2.53) |
 Western Europe | 99.5 (94.04–104.66) | 61.62 (56.85–66.77) | − 38.07 | 1.78 (1.69–1.87) | 0.69 (0.64–0.75) | − 4.12 (− 4.34 to − 3.89) |
 Western Sub-Saharan Africa | 4.74 (3.75–5.92) | 9.72 (7.87–12.33) | 105.04 | 0.43 (0.34–0.54) | 0.42 (0.33–0.52) | − 0.13 (− 0.16 to − 0.11) |