Fig. 7
From: miR-100 inhibits cell proliferation in mantle cell lymphoma by targeting mTOR
Upregulation of mTOR partially canceled the effects of miR-100 on decreasing the expression of mTOR mRNA and protein. a RT-PCR showed that the effects of miR‐100 on decreasing the expression of mTOR mRNA could be partially influenced by overexpression of mTOR in Jeko-1 cells (p < 0.0001). b RT-PCR showed that the effects of miR‐100 on decreasing the expression of mTOR mRNA could be partially influenced by overexpression of mTOR in Mino cells (p < 0.0001). c Western blot analysis of mTOR protein after PV-mTOR-up and LV-miR-100-up were cotransferred into the MCL cell lines. d The expression of mTOR protein in the LV-miR-up+PV-mTOR-up group was increased compared to the LV-miR-up+PV-NC-up group in Jeko-1 cells (p = 0.0287). e The expression of mTOR protein in the LV-miR-up+PV-mTOR-up group was increased compared to the LV-miR-up+PV-NC-up group in Mino cells (p = 0.0027).