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Fig. 5 | Experimental Hematology & Oncology

Fig. 5

From: Effects of decitabine on allogeneic immune reactions of donor lymphocyte infusion via activation of dendritic cells

Fig. 5

Effects of decitabine (DEC)-treated dendritic cells (DCs) on T cell proliferation and associated molecules. a Splenic DCs isolated from recipient mice treated with or without DEC were co-cultured with donor T cells, and proliferation of CD3 + , CD3 + CD4 + , and CD3 + CD8 + T cells was assessed via the carboxyfluorescein diacetate succinimidyl ester method. b Changes in the expression of molecules following DEC administration assessed using a gene kit of 84 genes known to be involved in DC function, and c the dynamics of IFN-γ and CD28 expression over time analyzed by real-time polymerase chain reaction

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