Fig. 2

The results of GSEA (GO terms). The gene profiles of samples with DACH1 low expression were significantly enriched in cell cycle G1-S transition (a), meiotic chromosome separation (b) and chromosome separation (c); The gene profiles of samples with DACH1 high expression were significantly enriched in mammary gland morphogenesis (d); The gene profiles of samples with EYA2 high expression were significantly enriched in (positive regulation) cell cycle G1-S transition (e and f), (positive regulation) NF-κB signaling pathway (g and h); positive regulation of Wnt pathway (i) and positive regulation of DNA repair pathway (j); The gene profiles of samples with SIX1 low expression were significantly enriched in (immune) response to tumor (k and l), positive regulation of cell killing (m), and T cell receptor pathway (n); The gene profiles of samples with SIX1 high expression were significantly enriched in base excision repair (o) and embryonic development (p)