Fig. 3

Somatic and immunogenic mutation alterations among three subtypes. Comparison of CNV burden fraction (a), Aneuploidy score (b), LOH segments (c), HRD score (d) among three clusters. e TP53 mutation frequency among three clusters (Chi-squared test, P < 0.05). Heatmap of significant amplification genes (f) and deletion genes (g) in each subtype (Chi-squared test or Fisher’s exact test, FDR < 0.1). ns: no significance, *P < 0.05, **P < 0.01, ***P < 0.001