Fig. 1
The subtypes of immune microenvironment in HCC. a Comparison of TME cells between HCC samples and adjacent tissues in multiple cohorts. Red: The abundance of TME cell is high in HCC tissues; Blue: The abundance of TME cell is low in HCC tissues; Green: No significance between HCC and non-tumor tissues. The size of the bubble means − log10 (FDR). Wilcoxon signed rank test was used to compare the significances of TME cell fractions between HCC samples and adjacent tissues. b Unsupervised clustering of TME cells in TCGA-LIHC with 374 patients. The representative anti-tumor (c) and immunosuppressive (d) characteristics among the three clusters. ns: no significance, *P < 0.05, **P < 0.01, ***P < 0.001