Frequent upregulation of G9a promotes RelB-dependent proliferation and survival in multiple myeloma

Table 2 Overall downregulated differentially genes from the pathway analysis (PANTHER pathway database)

	Pathway	Entities found	Genes	RNA expression (fold change)	p-values
1	Inflammation mediated by chemokine and cytokine signaling pathway (P00031)	5	ACTA2	0.330	0.0000675
			RELB	0.235	1.27E−11
			C5AR1	0.133	0.00286572
			ITGB7	0.491	0.000876315
			PRKACB	0.485	0.000301808
2	Apoptosis signaling pathway (P00006)	4	RELB	0.235	1.27E−11
			ATF4	0.419	0.00000206
			ATF3	0.352	0.000000508
			JDP2	0.278	0.00000913
3	Integrin signalling pathway (P00034)	3
4	p53 pathway (P00059)	3
5	Cholesterol biosynthesis (P00014)	3

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