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Fig. 4 | Experimental Hematology & Oncology

Fig. 4

From: Frequent upregulation of G9a promotes RelB-dependent proliferation and survival in multiple myeloma

Fig. 4

G9a depletion inhibit proliferation of MM cells in vivo. a Tumor volumes of KMS12BM xenografts with transfected shNT or shG9a lentivirus over time. (mean ± SD; *p < 0.05, ***p < 0.001 for both comparisons of shNT versus shG9a#1 and shG9a#2, Bonferroni corrected one-way ANOVA). b Final individual and mean tumor volumes of KMS12BM xenografts with transfected shNT or shG9a lentivirus at day 31. (Bonferroni corrected one-way ANOVA comparing all groups, ***p < 0.001). c Representative tumor images of KMS12BM MM xenografts with transfected shNT or shG9a lentivirus on day31. d Immunoblots show G9a expression level in representative KMS12BM xenograft tumors with transfected shNT or shG9a lentivirus

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