Fig. 1
From: Frequent upregulation of G9a promotes RelB-dependent proliferation and survival in multiple myeloma
G9a has high expression in multiple myeloma (MM) and regulates H3K9me2. a mRNA expression of EHMT2 in multiple myeloma cell lines and peripheral blood mononuclear cell (PBMC). (n = 3; mean ± SD; **p < 0.01 and ***p < 0.001). b Immunoblots show G9a in MM cell lines and PBMC. c Quantification of G9a band intensity relative to β-actin. (n = 2; mean ± SD; **P < 0.01 and ***p < 0.001). d Immunoblots show H3K9me2 and H3K9me1 in mm cell lines and PBMC. e Quantification of H3K9me1 and H3K9me2 bands intensity relative to total H3. f G9a expression and patient (ii) overall survival with p = 1.25 × 10−6 and (i) progression-free survival with p = 2.94 × 10−7 in CoMMpass data