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Table 2 Complications and prognosis of all patients between MSD and AD

From: Alternative donor peripheral blood stem cell transplantation for the treatment of high-risk refractory and/or relapsed childhood acute leukemia: a randomized trial

Variables

MSD (n = 42)

AD (n = 69)

χ2

P-value

Acute GVHD (n, %)

0.435

0.509

 Yes

15 (35.7)

29 (42.0)

 No

27 (64.3)

40 (58.0)

Grade II-IV aGVHD (n, %)

3.788

0.052

 Yes

2 (4.8)

12 (17.4)

 No

40 (95.2)

57 (82.6)

Chronic GVHD (n, %)

0.046

0.83

 Yes

9 (21.4)

16 (23.2)

 No

33 (78.6)

53 (76.8)

IPFD (n, %)

0.274

0.601

 Yes

12 (28.6)

23 (33.3)

 No

30 (71.4)

46 (66.7)

Hemorrhagic cystitis (n, %)

3.690

0.055

 Yes

8 (19.0)

25 (36.2)

 No

34 (81.0)

44 (63.8)

EBV infection (n, %)

17.674

< 0.001

 Yes

1 (2.4)

26 (37.7)

 No

41 (97.6)

43 (62.3)

CMV infection (n, %)

13.100

< 0.001

 Yes

9 (21.4)

39 (56.5)

 No

33 (78.6)

30 (43.5)

Relapse (n, %)

5.056

0.025

 Yes

19 (45.2)

17 (24.6)

 No

23 (54.8)

52 (75.4)

Death (n, %)

4.197

0.041

 Yes

16 (38.1)

14 (20.3)

 No

26 (61.9)

55 (79.7)

Non-relapse mortality (n, %)

4.051

0.044

 Yes

1 (6.3)*

5 (35.7)*

 No

15 (93.4)*

9 (64.3)*

  1. GVHD graft-versus-host disease, IPFD Invasive pulmonary fungal disease, EBV Epstein-Barr virus, CMV Cytomegalovirus; *Non-relapse mortality and relapse mortality as a percentage of total deaths