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Table 1 Clinical manifestations and cytogenetic abnormalities of MDS patients stratified by age groups

From: Gene mutational analysis by NGS and its clinical significance in patients with myelodysplastic syndrome and acute myeloid leukemia

 

Total patients (n = 93)

Younger MDS patients (n = 50)

Older MDS patients (n = 43)

p value

Age

46 (16–87 years)

43 (16–59 years)

69 (60–87 years)

N/A

Gender males (n, %)

56 (60.2%)

32 (64.0%)

24 (55.8%)

0.421

WBC (×109/L) (mean, range)

7.9 (0.3–123.9)

5.3 (0.7–123.9)

3.9 (0.3–11.1)

0.592

Hb (g/L) (mean, range)

79.1 (26.8–163.0)

80.1 (26.8–163.0)

77.9 (39.0–122.0)

0.701

Plate (×109/L) (mean, range)

75.9 (4.0–233.0)

71.9 (4.0–233.0)

80.4 (3.0–586.0)

0.661

Blast in BM (mean, range)

5.5 (0.2–18.9)

4.1 (0.2–16.4)

7.1 (0.4–18.9)

0.007**

  1. **Statistically singnificant difference (p < 0.01) was obseved between two groups