Fig. 3

Dacinostat and quisinostat induce G2/M arrest in Daoy and D283 cells. a, b Daoy and D283 cells were treated with dacinostat (0.1 µM for Daoy cells, 0.01 µM for D283 cells) or dacinostat (0.4 µM for Daoy cells, 0.04 µM for D283 cells) for 24 h and 48 h, respectively. The cell cycle distribution was analyzed by flow cytometry using FlowJo. c–f Histograms showing the percentage of Daoy and D283 cells in the subG1, G0–G1, S, and G2/M phases. g, h Percentage of cells in the G2/M phase. *P ≤ 0.05, **P ≤ 0.01, ***P ≤ 0.001. Experiments were performed three times, and values were presented as the mean ± SE