Fig. 1
From: Analysis of TET2 mutations in paroxysmal nocturnal hemoglobinuria (PNH)
Electropherograms demonstrate the presence of the 2697T>A (Y899X) mutation in blood cells from patient 14. a Sequences amplified from granulocytes from the initial blood sample. b–f Sequences amplified from cells from the third sample obtained 16 months after the initial blood sample: b sorted glycophorin A-positive nucleated red cells; c sorted CD33-positive Monocytes; d Granulocytes; e sorted FLAER-positive lymphocytes; f sorted FLAER-negative lymphocytes. The arrow indicates the peak at the 2697 position. The highest proportion of mutant sequences was seen amongst the monocytes